黃朝慶教授

  • Prof. Chao-Ching Huang

    小兒神經學、小兒癲癇、中樞神經感染、新生兒神經學

    研究方向:

    1. 熱性痙攣之臨床及動物實驗研究:研究熱性痙攣對兒童腦部海馬回之構造及其神經心智之影響;建立熱性痙攣動物模型,研究復發性熱性痙攣對幼鼠之影響;包括各種記憶行為,海馬回病變以及海馬回神經細胞可塑性改變之分子機轉,進一步探討影響其記憶行為改變之細胞信息傳導障礙以及其可能之藥物治療。
    2. 新生兒窒息腦病變之臨床及動物實驗研究:臨床上研究影響缺氧窒息是否會產生腦病變之各種缺氧調適分子之變化;動物實驗上研究對窒息產生 ischemic tolerance 及 pharmacologic tolerance 之重要細胞訊息傳導以及其分子基因調控變化,更進一步利用 cDNA microarray 雜交法及 proteomics 比較分析探討缺氧窒息及抗缺氧窒息之不同基因表現及重要 novel 蛋白質表現。
    3. 早產兒腦部白質軟化症之臨床及動物實驗研究:研究臨床上早產兒會發生白質病變及導致腦性麻痺之基因體研究;動物實驗上探討此腦部白質病變之病因及可以藥物治療之重要腦部保護之訊息傳遞路徑以及其分子調控變化。

    Selected publications:

  • Yi-Fang Tu, Ying-Chao Chang, Cheng-Yu Chen, Chao-Ching Huang. Neonatal neurological disorders involving brainstem: neurosonographic approaches through squamous suture and foramen magnum. Eur Radiol 2005 (in press) (Corresponding) [Abstract]

  • Chang YC, Kuo YM, Huang AM, Huang CC. (2005) Repetitive febrile seizures in rat pups cause long-lasting deficits in synaptic plasticity and NR2A tyrosine phosphorylation. Neurobiol Dis. 2005 Apr;18(3):466-75. [Abstract]

  • Lan-Wan Wang, Chao-Ching Huang, Tsu-Fu Yeh. Shan-Tair Wang. Concurrent and predictive validity of CAT/CLAMS for Bayley scales of infant development-II in very low-birth-weight infants before age two years. J Developmental & Behavioral Pediatrics (in press) (Corresponding) [Abstract]

  • Wen-Chau Wu, Chao-Ching Huang, Hsiao-Wen Chung, Michelle Liou, Chun-Jen Hsueh, Chang-Shin Lee, Ming-Long Wu, Cheng-Yu Chen. Hippocampal alterations in children with temporal lobe epilepsy with or without a history of febrile convulsions: Evaluations with MR volumetry and proton MR spectroscopy. AJNR Am J Neuroradiol (in press) [Abstract]

  • Tu YF, Chang YC, Chen CY, Huang CC. (2004) Acute flaccid paralysis due to myelopathy in childhood bacterial meningitis. Acta Paediatr Taiwan. 2004 May-Jun;45(3):158-62. Review. [Abstract]

  • Tu YF, Chen CY, Huang CC, Lee CS. (2004) Vacuolating megalencephalic leukoencephalopathy with mild clinical course validated by diffusion tensor imaging and MR spectroscopy. AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):1041-5. [Abstract]

  • Ting-Yu Lin, Chung-Hsin Chiang, Nai-Wen Guo, Chao-Ching Huang. Nonverbal communication skills of children with developmental disorders. Tzu-Chi Medical Journal (Taiwan) 2004;16:277-285. [Abstract]

  • Tsu-Fuh Yeh, Hung C Lin, Chao-Ching Huang. (2004) Postnatal dexamethasone for lung disease of prematurity. New England Journal of Medicine 2004;350:1715-1718. (Letter to editor) [Abstract]

  • Wang LW, Huang CC, Yeh TF. (2004) Major brain lesions detected on sonographic screening of apparently normal term neonates. Neuroradiology. 2004 May;46(5):368-73. Epub 2004 Apr 22. [Abstract]

  • Huang CW, Huang CC, Liu YC, Wu SN. (2004) Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells. Epilepsia. 2004 Jul;45(7):729-36. [Abstract]

  • Lee HT, Chang YC, Wang LY, Wang ST, Huang CC, Ho CJ. (2004) cAMP response element-binding protein activation in ligation preconditioning in neonatal brain. Ann Neurol. 2004 Nov;56(5):611-23. [Abstract]

  • Ying-Chao Chang, Chao-Ching Huang. Seizure-induced plasticity and adverse long-term effects of early-life seizures. Ann Neurol 2004:56:164-166. (Letter to editor) [Abstract]

  • Yeh TF, Lin YJ, Lin HC, Huang CC, Hsieh WS, Lin CH, Tsai CH. (2004) Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity. N Engl J Med. 2004 Mar 25;350(13):1304-13. [Abstract]

  • Chang YC, Huang AM, Kuo YM, Wang ST, Chang YY, Huang CC. (2003) Febrile seizures impair memory and cAMP response-element binding protein activation. Ann Neurol. 2003 Dec;54(6):706-18. [Abstract]

  • Chou IC, Peng CT, Huang CC, Tsai JJ, Tsai FJ, Tsai CH. (2003). Association analysis of gamma 2 subunit of gamma- aminobutyric acid type A receptor polymorphisms with febrile seizures. Pediatr Res. 2003 Jul;54(1):26-9. Epub 2003 Apr 02. [Abstract]

  • Chang YC, Guo NW, Wang ST, Huang CC, Tsai JJ. (2001). Working memory of school-aged children with a history of febrile convulsions: a population study. Neurology.2001 Jul 10;57(1):37-42. [Abstract]

  • Chang YC, Guo NW, Huang CC, Wang ST, Tsai JJ. (2000). Neurocognitive attention and behavior outcome of school-age children with a history of febrile convulsions: a population study. Epilepsia. 2000 Apr;41(4):412-20. [Abstract]

  • Huang CC, Liu CC, Chang YC, Chen CY, Wang ST, Yeh TF. (1999). Neurologic complications in children with enterovirus 71 infection. N Engl J Med. 1999 Sep 23;341(13):936-42. [Abstract]

  • Huang CC, Wang ST, Chang YC, Lin KP, Wu PL. (1999) Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. N Engl J Med. 1999 Jul 29;341(5):328-35. [Abstract]

  • Huang CC, Wang ST, Chang YC, Huang MC, Chi YC, Tsai JJ. (1999). Risk factors for a first febrile convulsion in children: a population study in southern Taiwan. Epilepsia. 1999 Jun;40(6):719-25. [Abstract]

  • Huang CC, Liu CC, Wang ST, Chang YC, Yang HB, Yeh TF. (1999). Basic fibroblast growth factor in experimental and clinical bacterial meningitis. Pediatr Res. 1999 Jan;45(1):120-7. [Abstract]


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    Updated: 5 Jul, 2012